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KMID : 1123920080220051309
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Korean Journal of Oriental Physiology and Pathology
2008 Volume.22 No. 5 p.1309 ~ p.1314
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Total Phenolic Contents, Radical Scavenging Capacities and Inhibitory Effects on Lipid Peroxidation and LDL Oxidation of Prunus persica Branch
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Yi Hyo-Seung
Moon Jin-Young
Park Won-Hwan
Lim Sun-Hee
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Abstract
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This study was undertaken to elucidate the antioxidant activity of the ethanol (EEPB) and water (WEPB) extracts of Prunus persica branches. The extracts contained a high phenolic content and revealed a potent hydrogen donating activity in DPPH scavenging assay. Compared to -tocopherol, EEPB (p < 0.001) and WEPB (p < 0.05) significantly inhibited -ascorbic acid-induced lipid peroxidation, and also exhibited potent antiradical activities against hydroxyl radical, superoxide anion, nitric oxide and peroxynitrite. In copper- and AAPH-mediated human low-density lipoprotein (LDL) oxidation systems, the extracts demonstrated a strong antioxidant function by metal chelating, rather than direct scavenging, action. Furthermore, EEPB at 5 concentration showed 80.77% inhibition of the electrophoretic mobility of LDL, compared to 77.69% for ascorbic acid and 76.92% for BHT. These results suggest that PB branch extracts may protect against oxidative stress-induced diseases
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KEYWORD
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Prunus persica antioxidant, lipid peroxidation low-density lipoprotein (LDL)
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